At the Bailis Lab, we want to learn how diet and metabolism control how the immune system behaves so we can better understand human health. Combining CRISPR screening, next-generation sequencing technologies, and metabolomics we aim to illuminate how the biochemistry of immune cells is as important as the genes they express. Our current major areas of focus are to understand the molecular mechanisms underlying:

1) how single-cell differences in metabolism control immune cell programming; 2) how immune cells adapt to dynamic nutrient environments and how this adaptation patterns future potential; 3) how chronic malnutrition dysregulates immune responses.